Chimeric lysin
WebApr 19, 2024 · In this study, a novel chimeric lysin, ClyC, was constructed by fusing the CD from the Ply187 lysin with the CBD from the LysSA97 lysin. The CD of Ply187 (1–157aa, Ply187N) was chosen because it has been shown to have much higher activity compared to its parental full length S. aureus phage Ply187 [ 25 ]. WebSep 15, 2014 · In the present work, a novel chimeric lysin (Ply187N-V12C) was constructed by fusing Ply187N with the CBD (146-314aa, V12C) of PlyV12 to test if the lytic specificity of Ply187N would be extended to …
Chimeric lysin
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WebAug 24, 2024 · Lysine is an herbal supplement used for athletic performance enhancement, or treatment for cold sores (herpes simplex libialis) and elevated pH (metabolic … WebJan 9, 2024 · Yang, H. et al. Novel chimeric lysin with high-level antimicrobial activity against methicillin-resistant Staphylococcus aureus in vitro and in vivo. Antimicrob. Agents Chemother. 58 , 536–542 ...
WebFeb 10, 2024 · The control was performed without chimeric lysin. (A) Changes in total viable counts in the chilled chicken during storage at 4 °C for 14 days. (B) Changes in the pH of the chilled chicken during ... WebFeb 1, 2024 · Chimeric ClyV lysin (obtained by fusion of the enzymatically active domain from PlyGBS lysin and the cell wall binding domain from PlyV12 lysin) presented improved bactericidal activity in vitro ...
WebApr 15, 2024 · Previously, we reported a broad-spectrum chimeric lysin, ClyR, with a cysteine, histidine-dependent amidohydrolase/peptidase catalytic domain from PlyC lysin and an SH-3b cell-wall binding domain from PlySs2 lysin. Herein, we further report that a novel internal cell-penetrating peptide (CPP) is predicted in the junction region of the two ... WebSep 15, 2014 · Developing chimeric lysins with a wide lytic spectrum would be important for treating some infections caused by multiple pathogenic bacteria. In the present work, a novel chimeric lysin (Ply187N-V12C) …
WebJun 5, 2024 · A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae. J. Antimicrob. Chemother. 70, 1763–1773. 10.1093/jac/dkv038 [Google Scholar] Domenech M., García E., Moscoso M. (2011).
WebLysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic … iron chef sayingsWebJan 9, 2024 · A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus Methicillin-resistant Staphylococcus … port number to voip.msWebMar 27, 2024 · In addition, the chimeric lysin, ClyJ, was constructed by fusing GPB coding sequence to the C terminus of the CHAP domain of PlyCA (amino acids 314 to 465) using sequence-specific primers (Table S4). The pneumococcal Cpl-1 lysin coding sequence was chemically synthesized by GenScript (Nanjing, China) and cloned into a pET28b(+) … port number to verizon wireless prepaidWebNov 16, 2024 · Cationic peptide chimeric lysins, Lysqdvp001-5aa, Lysqdvp001-10aa and Lysqdvp001-15aa, were designed based on lysin Lysqdvp001 from Vibrio parahaemolyticus (V. parahaemolyticus) phage qdvp001.These chimeric lysins showed equivalent peptidoglycan hydrolysis activities with Lysqdvp001 and could lyse the bacteria from the … iron chef season 7 episode 39WebMay 25, 2024 · A newly evolved chimeric lysin motif receptor-like kinase in Medicago truncatula spp. tricycla R108 extends its Rhizobia symbiotic partnership. ... Using genomics and reverse genetics, we identified a newly evolved, chimeric LysM receptor-like kinase gene in R108, LYK2bis, ... iron chef showdownWebMay 15, 2024 · Activation of the immune system using antigen targeting to the dendritic cell receptor DEC205 presents great potential in the field of vaccination. The objective of this work was to evaluate the immunogenicity and protectiveness of a recombinant mouse x pig chimeric antibody fused with peptides of structural and nonstructural proteins of porcine … iron chef secret ingredientWebJan 9, 2024 · Developing chimeric lysins (chimeolysins) by shuffling these two domains from different natural lysins has been demonstrated to be a … iron chef sesame garlic sauce