Cisplatin and electrolyte abnormalities
WebNov 1, 2024 · Vaughn E. Dobalian Abstract and Figures Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia,... WebA slight electrolyte imbalance may not cause noticeable changes. When problems occur, you may experience: Confusion and irritability. Diarrhea or constipation. Fatigue. Headaches. Irregular or fast heart rate (arrhythmia). Muscle cramps, muscle spasms or weakness. Nausea and vomiting. Numbness or tingling in limbs, fingers and toes.
Cisplatin and electrolyte abnormalities
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WebMay 18, 2024 · Compared with young patients, the incidences of cisplatin-induced nephrotoxicity and acute kidney injury (AKI) in elderly patients are significantly increased, … WebMay 7, 2024 · For the approximately 30% of patients with SCLC who have limited-stage disease at the time of diagnosis (ie, tumors confined to the hemithorax of origin, the …
WebFrequent grade 3 or 4 adverse events included fatigue, dyspnea, leukopenia, thrombocytopenia, and electrolyte abnormalities. No objective responses were observed; 5 (50%) of 10 patients treated at the MTD had stable disease. Pharmacokinetics indicated an oral triapine bioavailability of 88%. WebMagnesium depletion usually results from inadequate intake plus impairment of renal conservation or gastrointestinal absorption. There are numerous causes of clinically significant magnesium deficiency (see table Causes of Hypomagnesemia Causes of Hypomagnesemia ).Hypomagnesemia is common among hospitalized patients and …
Webcisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric Dosage … WebJan 1, 2015 · Cisplatin administration is commonly associated with electrolyte imbalance. Careful monitoring of renal function and serum electrolytes is therefore essential in this setting.
WebAbstract Cisplatin is a widely used platinum‐based chemotherapy agent. Its common adverse effects are neuropathy, nephrotoxicity, electrolyte abnormality, and rarely causing thrombotic vascular toxicity. We present a patient known to have small‐cell lung cancer who developed ischemic cerebrovascular accident (CVA) after receiving ...
WebJan 17, 2015 · In this research, we focused only on electrolyte abnormalities following cisplatin toxicity, to predict electrolyte abnormalities occurred in dogs treated with cisplatin. The present study was carried out to evaluate renal function of dogs administered with cisplatin 0.75 mg/kg/day for 5 consecutive days with assaying of electrolytes and … the patch estrogenWebAug 26, 2024 · Electrolyte disturbances can be caused by infections, medicines, trauma and surgery; poor nutritional intake and malabsorption can also contribute to deficiencies [3] . The exact incidence of electrolyte disturbances in the UK is difficult to define, as individual studies have tended to focus on the occurrence in discrete populations [4,5] . the patch essex ctWebJul 18, 2024 · Cisplatin causes hypomagnesemia in a dose-dependent fashion and affects up to 90% of patients if no preventive measures are taken (see Section 5 below). 79 The etiology of cisplatin-induced hypomagnesemia is not completely understood; renal Mg loss is the primary mechanism, but gastrointestinal losses have also been reported. 80 … shwu yin project managerWebCisplatin is a coordinate metal complex with significant antineoplastic activity and various effects, including acute anc chronic renal insufficiency and renal magnesium wasting. … the patch evergreen park illinoisWebHypomagnesemia may cause nausea, vomiting, sleepiness, weakness, personality changes, muscle spasms, tremors, and loss of appetite. If severe, hypomagnesemia can cause seizures Seizure Disorders In seizure disorders, the brain's electrical activity is periodically disturbed, resulting in some degree of temporary brain dysfunction. Many … shw valuers brighton u.kWebFurosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, ... Abnormalities should be corrected or the drug temporarily withdrawn. Other medications may also influence serum electrolytes. ... There is a risk of ototoxic effects if cisplatin and ... the patch estate wollertWebJul 20, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, … shw vista l shape desk with monitor stand