WebIn mammalian cells, YAP induces Birc5 and Birc2 ( Dong et al. 2007 ), two diap1 homologs, and many cytokines such as connective tissue growth factor (CTGF), brain-derived neurotrophic factor (BDNF), fibroblast growth factor 1 (FGF1), and amphiregulin (AREG) ( Hao et al. 2008; Zhao et al. 2008; J Zhang et al. 2009, although their contribution to … WebSep 20, 2024 · To evaluate the role of Akt in YAP activation in TGF-β1-treated MCs, cells were treated with the Akt inhibitor MK-2206, which resulted in reduced YAP expression …
Role of mechanotransduction mediated by YAP/TAZ in the
WebFeb 13, 2024 · 3.3. CAP Accelerates Migration through the Activation of the YAP-CTGF-Cyr61 Axis. Quantitative real-time PCR revealed that CAP significantly stimulated YAP … WebMay 12, 2024 · We studied the mechanism for the regulation of YAP expression following different periods of serine deprivation. YAP underwent a significant decrease in the first 2 days of serine withdrawal; this was followed by a clear increase in protein expression . CTGF expression followed the changes in YAP (Supplementary Figure 5A). After … imitation flagstone flooring
The HIPPO Transducer YAP and Its Targets CTGF and …
WebIncreasing numbers of Ctgf-expressing periportal hepatocytes in DDC-treated compared with naive mice indicates activation of YAP signaling in response to injury (Figures 2A and 2B). Although control mice showed a substantial increase in SOX9+ periportal hepatocytes 14 days or 6 weeks post-DDC damage, Yap DEL mice did not show an increase ... WebApr 12, 2024 · Intracavernosal pressure/mean arterial pressure (ICP/MAP) was measured 14 and 28 days after treatment. Penile tissue specimens were collected for pathological examination, and the changes in YAP, TAZ, CTGF, CYR61, LATS1, and p38 MAPK expression levels were assessed by Western blot, RT–qPCR and immunological … WebApr 12, 2024 · The volcano plot revealed a significant increase in the expression of CTGF and CYR61 downstream of YAP as a result of USP1 depletion. Threshold values of P < 0.05 and fold change>2 was set as ... imitation flame light bulbs