Equipoise definition in research
WebMar 18, 2004 · The concept of 'equipoise', or the 'uncertainty principle', has been represented as a central ethical principle, and holds that a subject may be enrolled in a randomized controlled trial (RCT) only if there is true uncertainty about which of the trial arms is most likely to benefit the patient. WebJan 10, 2012 · Despite its intuitive appeal, clinical equipoise is beset by serious conceptual and practical problems. 14,15 First and most fundamental, it imposes the ethics of medical care on the design and ...
Equipoise definition in research
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Web1. equal distribution of weight; state of balance, or equilibrium 2. a weight or force that balances another; counterbalance Webster’s New World College Dictionary, 4th Edition. …
WebThe principle of equipoise states that if there is uncertainty or conflicting expert opinion about the relative therapeutic, prophylactic or diagnostic merits of a set of interventions, it is permissible to allocate a participant to receive an intervention from this set, so long as there is no consensus that an alternative intervention would bet... Web1 : a state of equilibrium 2 : counterbalance equipoise 2 of 2 verb equipoised; equipoising; equipoises transitive verb 1 : to serve as an equipoise to 2 : to put or hold in equipoise …
WebClinical equipoise is widely regarded as an ethical requirement for the design and conduct of RCTs. Underlying clinical equipoise is the norm that no patient should be randomized … Webrefers to a series of analytical steps that must be performed by a VA decision maker in making findings of fact for the purpose of drawing conclusions of law on each aspect or criterion of the legal standard for entitlement to the benefit and on applicable procedural matters. Follow the steps in the table below when evaluating evidence: Reference
WebFeb 7, 2024 · Equipoise in Research: Integrating Ethics and Science in Human Research JAMA. 2024 Feb 7;317(5):525-526. doi: 10.1001/jama.2024.0016. Author Alex John London 1 Affiliation 1 Department of Philosophy, Carnegie Mellon University, Pittsburgh, Pennsylvania. PMID: 28170466 DOI: 10.1001 ...
Webnoun. an equal distribution of weight; even balance; equilibrium. a counterpoise. verb (used with object), e·qui·poised, e·qui·pois·ing. to equal or offset in weight; balance. huit in french translationWebequipoise noun [ U ] formal uk / ˈek.wɪ.pɔɪz / us / ˈek.wɪ.pɔɪz / a situation in which things are perfectly balanced: There is in the artist's landscapes a delicate equipoise between … huitink groenlo occasionsWebDec 28, 2024 · Equipoise and the Ethical Justification of RCTs. It is true that not all of the feasible randomized clinical trials (RCTs) that physicians can imagine running are ethically justified, and therefore some set of principles or criteria must be formulated in order to decide which RCTs should proceed. Clinical equipoise is one such criterion, but we ... huit financial applicationsWebThe ethics of clinical research requires equipoise — a state of genuine uncertainty on the part of the clinical investigator regarding the comparative therapeutic merits of each arm in a trial ... huitink garage occasionsWebEquipoise is defined as a state of professional uncertainty about the relative therapeutic merits of treatments provided to patients. The principle of equipoise states that if there is … huitian face masksWebOct 2, 2012 · e·qui·poise ( e'kwi-poyz ), 1. Equilibrium; an even distribution of weight. 2. In epidemiology, a state of uncertainty as to the balance of benefits and harm that may … huitlacoche control measuresWebThe ethics of clinical research requires equipoise — a state of genuine uncertainty on the part of the clinical investigator regarding the comparative therapeutic merits of each arm in a trial.... huit laboratories inc