Ifitm1 and cancer
Web28 jul. 2024 · IFITM1 overexpression is confirmed in the AI-resistant MCF-7:5C cell line and not found in AI-sensitive MCF-7 cells. In this study, the orthotopic (mammary fat … Web9 apr. 2024 · HIV-1 is a complex retrovirus that is adapted to replicate in cells of the immune system. To do so, HIV-1, like other viruses, developed strategies to use several cellular processes to its advantage, but had also to come to terms with an arsenal of cellular innate defense proteins, or antiviral factors, that target more or less efficiently, virtually every …
Ifitm1 and cancer
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Web22 mrt. 2024 · The genes in this signature, SEL1L3, HAPLN3, BST2, and IFITM1, may be functionally involved in melanoma progression and immune response. These findings suggest that this four-gene signature has... WebAlthough IFITM1 overexpression enhanced CD81 expression, IFITM1 knockdown did not affect CD81 expression (Fig. 4C). To know the role of CD81 for the invasion of HNSCC cells, we examined the ...
WebIn a previous study, we showed that IFITM1 is involved in the immune escape and metastasis of gastric cancer cells. In this study, we determined the difference in … Web14 dec. 2024 · Pan-cancer analysis of the prognostic value of IFITM1. We assessed the prognostic value of IFITM1 in multiple types of cancer. As shown in Supplementary Figure S6, Kaplan–Meier survival analysis revealed that the low expression of IFITM1 was associated with poor overall survival in BRCA (p = 0.031); the upregulation of IFITM1 …
WebInterferon-inducible transmembrane (IFITM) proteins are a family of small homologous proteins, localized in the plasma and endolysosomal membranes, which confer cellular … Web7 jul. 2024 · IFITM1 knockdown diminishes AI-resistant tumor growth and invasion in vivo which is associated with changes in CD31+ blood vessel density and matrix …
WebIn colon (4), breast (19), and lung cancers (20), IFITM1 is highly expressed and has a cancer-promoting effect. However, IFITM1 has a low expression in cervical squamous cell carcinoma and a...
Web7 jan. 2024 · IFITM1 promotes homotypic adhesion of lymphocytes and inhibits proliferation of the B cell lineage [ 14, 15 ]. In addition, IFITM1 has been implicated in the migration, invasion, and proliferation of cancer cells [ 16, 17] but can also inhibit tumor cell growth [ 18 ]. ed smith cowboysWebIn molecular biology, housekeeping genes are typically constitutive genes that are required for the maintenance of basic cellular function, and are expressed in all cells of an organism under normal and patho … ed smith decision makingWeb2 dec. 2024 · Interferon-inducible transmembrane (IFITM) proteins are a family of small homologous proteins, localized in the plasma and endolysosomal membranes, which confer cellular resistance to many viruses. In addition, several distinct functions have been associated with different IFITM family members, including germ cell specification … ed smith cherry pie filling recipesWeb21 mrt. 2024 · IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. Diseases associated with IFITM1 include Influenza and West Nile Virus . Among … constraints foreign key mysqlWeb29 mrt. 2024 · Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer. Differential Leukocyte Expression of IFITM1 and IFITM3 in Patients with Severe Pandemic Influenza A (H1N1) and COVID-19. Impact of interferon-induced transmembrane protein 3 gene rs12252 polymorphism on … constraints in a design briefWeb1 jan. 2024 · IFITM1 was found to interact with the cytoplasmic splicing factor protein SRSF1 in a cervical carcinoma cell line and was found to directly interact with HLA-B mRNA … constraints in frenchWeb18 feb. 2024 · Many cancer therapies aim to trigger apoptosis in ... W. et al. Human papillomavirus downregulates the expression of IFITM1 and RIPK3 to escape from IFNγ- and TNFα-mediated antiproliferative ... ed smith delaware