WebIron storage proteins, ferritin (Ftn) and bacterioferritin (Bfr), are dynamic regulators of iron levels in bacteria. Ftn and Bfr appear to be essential for the survival and virulence of … WebOct 25, 2005 · Iron-storage protein, whose ferroxidase center binds Fe 2+ ions, oxidizes them by dioxygen to Fe 3+, and participates in the subsequent Fe 3+ oxide mineral core formation within the central cavity of the protein complex. The mineralized iron core can contain as many as 2700 iron atoms/24-meric molecule. 2 publications Miscellaneous
Bacterioferritin: A Microbial Iron-Storage Protein?
WebDec 16, 1994 · Crystals of E. coli cytochrome b1, alias bacterioferritin, were grown fr om a low ionic strength solution. The resulting monoclniic P21 structure was solved by molecular replacement and refined using noncrystallographi c symmetries applied to the fundamental unit, consisting of two protein subunits and a single haem. WebAug 14, 2024 · Bacterioferritin (Bfr, encoded by bfr) regulates the storage and utilization of iron, which is essential for the growth and metabolism of microorganisms. However, the … baukran potain 331b
Frontiers Iron–Sulfur Cluster Biogenesis and Iron Homeostasis in ...
WebApr 1, 2015 · The iron storage protein bacterioferritin (Bfr) has the unique property of binding 12 heme groups in its protein shell. We substituted the hemes with the well-known photosensitizer, zinc protoporphryin IX and loaded the inner cavity of Bfr with ~1000 irons as a ferric oxyhydroxide polymer. We also fused the RGD4C tumor-targeting peptide to the ... WebJun 10, 2016 · The bfr gene encodes the iron storage protein bacterioferritin, and its expression is derepressed by iron. An mbfA bfr double mutant showed a loss of stress adaptation, and had a severe growth phenotype in high iron media. Moreover, a bfr up allele in which bfr is constitutively derepressed conferred stress tolerance on an mbfA mutant … WebJan 6, 2024 · Iron storage capacities of BfrA and BfrB. Purified proteins were incubated separately with increasing amounts of iron for 2 hours at room temperature to facilitate the storage of iron as ferric ... baukranen